AGE DIFFERENCES IN PATIENTS WITH TYPE B AORTIC DISSECTION

Abstract

Objectives: This study aims to retrospectively review the clinical data of patients with Type B aortic dissection from a single center, in order to investigate the potential associations between clinical characteristics, treatment modalities, and age. The findings of this study are intended to provide novel insights for clinical management and prognostic evaluation. Methods: Collected clinical data of patients with Type B aortic dissection who were admitted to our center from January 1, 2022, to December 31, 2022, and analyzed the clinical characteristics and treatments of the patients by age group. Results: A total of 190 inpatient cases of Type B aortic dissection were identified in 2022; after applying inclusion and exclusion criteria, 135 patients were included. Patients were divided into ≤60 years (n=87) and >60 years (n=48) groups. Males accounted for 81.5% (110/135), with significant gender distribution differences between age groups (p<0.001). Hypertension was the most prevalent comorbidity (92.6%), and significant differences were observed for diabetes, atherosclerosis, and myocardial infarction between age groups (p<0.05). D-dimer median levels were significantly higher in the >60 years group (3.9 mg/L) than in the ≤60 years group (2.5 mg/L) (p=0.024). Treatment modality differed significantly between groups (p=0.014), with conservative treatment more common in the >60 years group (37.5%) versus the ≤60 years group (18.4%). Conclusion: TBAD incidence is four times higher in males, but the female proportion increases with age. Hypertension is the main risk factor, endovascular treatment is preferred overall, but elderly patients tend toward conservative management. Future research should further clarify age- and intervention-specific effects on outcomes.